

Syn-Ake Topical (200mg)
Syn-Ake Topical (200mg) is a topical peptide formulation for dermal research applications, HPLC-MS verified above 99% purity.
This product is currently out of stock. Email us to check the next available batch.
View wholesale pricing →Syn-Ake Topical (200mg) is a lyophilized research peptide synthesized, purified, and lyophilized in the USA. Each production batch is purified by repeated rounds of reverse-phase HPLC and identity-confirmed by mass spectrometry.
Current evaluation of Syn-Ake Topical (200mg) explores its compatibility with common formulation excipients used in cosmetic research.
Syn-Ake Topical (200mg) is a cosmetic-research peptide evaluated in formulations for its signaling effects on skin-related cell models.
Studies of Syn-Ake Topical (200mg) typically focus on collagen-related or matrix-associated endpoints in dermal cell cultures.
Each vial contains lyophilized peptide at the labeled quantity, and wholesale orders are packed in boxes of ten vials at a single per-vial price.
Quality assurance: every batch is purified by reversed-phase high-performance liquid chromatography and identity-confirmed by mass spectrometry, with purity above 99%. Lot-specific certificates of analysis are available on request. Store lyophilized vials at -20°C, protected from light and moisture; reconstitute with bacteriostatic water immediately before use and avoid repeated freeze-thaw cycles. For in-vitro laboratory research use only —not for human or veterinary use.
Research & Literature
The following peer-reviewed studies and reference documents are commonly consulted by researchers working with Syn-Ake Topical (200mg). Summaries are provided for orientation only and reflect the cited sources.
Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy[1] —This review discusses cosmeceutical peptides within the wellness economy framework, including snake-venom-mimetic peptides such as Syn-Ake. The authors examine how these neurotransmitter-inhibitor peptides are proposed to relax facial muscles and reduce expression wrinkles. They evaluate the evidence base for such activities and consider the role of these actives in modern skin care. (Frontiers in Chemistry 2020)
Signal Peptides - Promising Ingredients in Cosmetics[2] —This review surveys signal peptides and related bioactive peptides as promising cosmetic ingredients. The authors discuss neurotransmitter-modulating peptides, including mimetics of snake venom components, and their proposed roles in anti-aging skin care. They highlight the mechanisms by which such peptides may influence skin appearance and the challenges of establishing their efficacy. (Current Protein & Peptide Science 2021)
Role of topical peptides in preventing or treating aged skin[3] —This comprehensive review examines the role of topical peptides in preventing and treating aged skin. The authors evaluate clinical evidence for several peptide categories, including neurotransmitter-inhibitor peptides such as Syn-Ake. They discuss the proposed mechanisms of action and the strength of clinical data supporting these ingredients in anti-aging formulations. (International Journal of Cosmetic Science 2009)
References
- Errante F, Ledwoń P, Latajka R, Rovero P, Papini AM. "Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy." Frontiers in Chemistry. 2020. public-pages-files-2025.frontiersin.org/journals/chemistry/articles/10.3389/fchem.202—
- Skibska A, Perlikowska R. "Signal Peptides - Promising Ingredients in Cosmetics." Current Protein & Peptide Science. 2021. pubmed.ncbi.nlm.nih.gov/34382523/
- Gorouhi F, Maibach HI. "Role of topical peptides in preventing or treating aged skin." International Journal of Cosmetic Science. 2009. pubmed.ncbi.nlm.nih.gov/19570099/
All products are supplied as lyophilized powder for in-vitro laboratory research use only and are not for human or veterinary use.
| SKU | TOP-SYNAKE-200 |
| Category | Peptides |
| Form | Lyophilized powder |
| Other Names | Dipeptide Diaminobutyroyl Benzylamide Diacetate, SYN-AKE |
| Purity | > 99% (HPLC-MS verified) |
| Storage | Store lyophilized at -20°C, protected from light |
Which research areas commonly use Syn-Ake Topical (200mg)?
Syn-Ake Topical (200mg) is most often referenced in studies related to dermal cell models and cosmetic-formulation research. Typical laboratory protocols combine dose-response assays with purity verification before experimental application.
What is the purity of Syn-Ake Topical (200mg)?
All batches are purified by reversed-phase HPLC and identity-confirmed by mass spectrometry, with purity above 99%. Lot-specific certificates of analysis are available on request.
How is Syn-Ake Topical (200mg) packaged?
Each vial contains lyophilized peptide at the labeled quantity. Wholesale orders are packed in boxes of ten vials at a single per-vial price.
How should Syn-Ake Topical (200mg) be stored?
Store lyophilized vials at -20°C, protected from light and moisture. Reconstitute with bacteriostatic water immediately before use and avoid repeated freeze-thaw cycles.
Is Syn-Ake Topical (200mg) for human or veterinary use?
No. All products are supplied for in-vitro laboratory research use only and are not for human or veterinary use.
Batch Certificates of Analysis
Every production batch of this product is analyzed by HPLC (purity) and mass spectrometry (identity). Certificates accompany each order and are available on request for any batch.
- HPLC-UV purity report with chromatogram
- MS identity report with molecular weight confirmation
Batch Documentation
Batch documentation is available on request. Certificates from an accredited laboratory are published here once issued.
Lyophilized Powder
Supplied as lyophilized powder for in-vitro laboratory research use.
Purity Specification
Purity specification above 99% by HPLC-MS, as listed on each product page.
Wholesale Box Pricing
One box = ten vials at a single per-vial rate, with volume pricing for labs and distributors.


