

Nonapeptide-1 Topical (200mg)
Nonapeptide-1 Topical (200mg) is a topical peptide formulation for dermal research applications, HPLC-MS verified above 99% purity.
This product is currently out of stock. Email us to check the next available batch.
View wholesale pricing →Nonapeptide-1 Topical (200mg) is a lyophilized research peptide synthesized, purified, and lyophilized in the USA. Each production batch is purified by repeated rounds of reverse-phase HPLC and identity-confirmed by mass spectrometry.
Nonapeptide-1 Topical (200mg) is often screened alongside other matrix peptides to compare activity profiles in vitro.
Laboratory work on Nonapeptide-1 Topical (200mg) emphasizes controlled concentration studies and reproducible assay conditions.
Current evaluation of Nonapeptide-1 Topical (200mg) explores its compatibility with common formulation excipients used in cosmetic research.
Each vial contains lyophilized peptide at the labeled quantity, and wholesale orders are packed in boxes of ten vials at a single per-vial price.
Quality assurance: every batch is purified by reversed-phase high-performance liquid chromatography and identity-confirmed by mass spectrometry, with purity above 99%. Lot-specific certificates of analysis are available on request. Store lyophilized vials at -20°C, protected from light and moisture; reconstitute with bacteriostatic water immediately before use and avoid repeated freeze-thaw cycles. For in-vitro laboratory research use only —not for human or veterinary use.
Research & Literature
The following peer-reviewed studies and reference documents are commonly consulted by researchers working with Nonapeptide-1 Topical (200mg). Summaries are provided for orientation only and reflect the cited sources.
Melanocortin 1 Receptor (MC1R): Pharmacological and Therapeutic Aspects[1] —This review examined the pharmacological and therapeutic aspects of the melanocortin 1 receptor (MC1R), the receptor targeted by alpha-MSH-mimetic peptides such as nonapeptide-1. The authors discussed the receptor's roles in melanin pigmentation regulation and its broader biology. The review indicated that MC1R is a key target for peptides intended to modulate skin pigmentation. (International Journal of Molecular Sciences 2023)
Bioactive oligopeptides in dermatology: Part I[2] —This review discussed bioactive oligopeptides used in dermatology, focusing on agents that modulate melanin synthesis. The authors placed peptides such as nonapeptide-1 (Melitane) within this mechanistic class of skin-lightening actives. The review suggested that melanin-modulating oligopeptides represent a growing category of dermatological ingredients. (Experimental Dermatology 2012)
Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy[3] —This review surveyed cosmeceutical peptides in the context of a sustainable wellness economy, including depigmenting and melanocortin-related peptides used in cosmetics. The authors discussed how peptide actives such as nonapeptide-1 are developed and positioned as cosmetic ingredients. The review indicated that melanocortin-related peptides continue to attract interest for skin-brightening applications. (Frontiers in Chemistry 2020)
References
- Mun Y, Kim W, Shin D. "Melanocortin 1 Receptor (MC1R): Pharmacological and Therapeutic Aspects." International Journal of Molecular Sciences. 2023. pubmed.ncbi.nlm.nih.gov/37569558/
- Reddy B, Jow T, Hantash BM. "Bioactive oligopeptides in dermatology: Part I." Experimental Dermatology. 2012. pubmed.ncbi.nlm.nih.gov/22672743/
- Errante F, Ledwoń P, Latajka R, Rovero P, Papini AM. "Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy." Frontiers in Chemistry. 2020. public-pages-files-2025.frontiersin.org/journals/chemistry/articles/10.3389/fchem.202—
All products are supplied as lyophilized powder for in-vitro laboratory research use only and are not for human or veterinary use.
| SKU | TOP-NP1-200 |
| Category | Peptides |
| Form | Lyophilized powder |
| Other Names | Melitane, Nonapeptide 1 |
| Purity | > 99% (HPLC-MS verified) |
| Storage | Store lyophilized at -20°C, protected from light |
Which research areas commonly use Nonapeptide-1 Topical (200mg)?
Nonapeptide-1 Topical (200mg) is most often referenced in studies related to dermal cell models and cosmetic-formulation research. Typical laboratory protocols combine dose-response assays with purity verification before experimental application.
What is the purity of Nonapeptide-1 Topical (200mg)?
All batches are purified by reversed-phase HPLC and identity-confirmed by mass spectrometry, with purity above 99%. Lot-specific certificates of analysis are available on request.
How is Nonapeptide-1 Topical (200mg) packaged?
Each vial contains lyophilized peptide at the labeled quantity. Wholesale orders are packed in boxes of ten vials at a single per-vial price.
How should Nonapeptide-1 Topical (200mg) be stored?
Store lyophilized vials at -20°C, protected from light and moisture. Reconstitute with bacteriostatic water immediately before use and avoid repeated freeze-thaw cycles.
Is Nonapeptide-1 Topical (200mg) for human or veterinary use?
No. All products are supplied for in-vitro laboratory research use only and are not for human or veterinary use.
Batch Certificates of Analysis
Every production batch of this product is analyzed by HPLC (purity) and mass spectrometry (identity). Certificates accompany each order and are available on request for any batch.
- HPLC-UV purity report with chromatogram
- MS identity report with molecular weight confirmation
Batch Documentation
Batch documentation is available on request. Certificates from an accredited laboratory are published here once issued.
Lyophilized Powder
Supplied as lyophilized powder for in-vitro laboratory research use.
Purity Specification
Purity specification above 99% by HPLC-MS, as listed on each product page.
Wholesale Box Pricing
One box = ten vials at a single per-vial rate, with volume pricing for labs and distributors.


